In which of the following situations, a poor increment in platelet count is expected after platelet transfusion?
A- Previous splenectomy
B- A patient with liver transplantation
C- Thin and short patient
D- Corticosteroid use
E - Aspirin use
Check the answer and explanation, below
Answer : B
Explanation:
Splencetomy is associated with thrombocytosis. Hyperspleneism is associated with
thrombocytopenia and less favorable response to platelet transfusion.
Organ transplanatation in general is
associated with p[latelet alloimmunization and week response to platelet
transfusion, usually by formation of antibodies directed against HLA antigens.
Other causes of alloimmunization are previous transfusions, pregnancy,
and organ transplantation.
Corticosteroids can improve response
to platelet transfusion in patients with immune thrombocytopenia.
Aspirin impairs platelet aggregation
and doesn't affect platelet count.
No comments:
Post a Comment